Jaguars at Texans: Predictions, picks and odds for NFL Week 10 game

The Jacksonville Jaguars (5-3) visit the Houston Texans (3-5) at NRG Stadium in Houston for a Week 10 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, November 9, including live updated odds and injury report news.
NameWeek 92025 SeasonJon Hoefling7-769-63-3Tyler Dragon6-868-64-3Blake Schuster10-465-54-3Lorenzo Reyes6-863-71-3Chris Bumbaca5-959-73-3Jordan Mendoza7-753-50-2Richard MorinN/A25-12-1
Texans vs. Jaguars live odds, moneyline, over/under
Opening Lines
- Spread: Houston Texans (-3.5)
- Moneyline: Houston Texans (-182), Jacksonville Jaguars (+152)
- Over/Under: 45.5
Get the edge with our exclusive NFL betting picks
Texans vs. Jaguars picks against the spread
Tyler Dragon: Houston Texans (-1)
This is a pick ’em game. The point spread illustrates that. The Texans have to start winning some games or else there really will be a problem in H-Town.
Jon Hoefling: Houston Texans (-1)
Both teams are coming off very close losses that probably both should have been wins. That makes this one a very difficult game to pick. I’ll choose the team that just held Denver to 18 points.
Jordan Mendoza: Houston Texans (-1)
It’s become clear the Texans will only go as far as their offense can, especially if C.J. Stroud is able to play. It should be a little bit more productive against a unit that had some difficulty against the Raiders.
Blake Schuster: Jacksonville Jaguars (+1)
There is nothing about this Texans team that makes me comfortable at this point. Meanwhile, Jacksonville adding Jakobi Meyers is an intriguing wrinkle on offense.
Lorenzo Reyes: Jacksonville Jaguars (+1)
With C.J. Stroud in concussion protocol early in the week, I’d monitor this until later if you’re considering Houston. Still, with that uncertainty, I’ll back the Jags here. The move, frankly, might be the under, even though it’s as low as 38.5, as of this writing.
Christopher Bumbaca: Jacksonville Jaguars (+1)
One of the toughest games of the week to pick. Rolling with the Jaguars here because of QB uncertainty in Houston.
Texans vs. Jaguars updated injury report
NFL Week 10 picks, predictions odds
Raiders at Broncos | Falcons at Colts | Bills at Dolphins | Giants at Bears | Saints at Panthers | Browns at Jets | Jaguars at Texans | Patriots at Buccaneers | Ravens at Vikings | Cardinals at Seahawks | Lions at Commanders | Rams at 49ers | Steelers at Chargers | Eagles at Packers




