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Chargers at Jaguars: Predictions, picks and odds for NFL Week 11 game

The Los Angeles Chargers (7-3) visit the Jacksonville Jaguars (5-4) at EverBank Stadium in Jacksonville for a Week 11 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, November 16, including live updated odds and injury report news.

NameWeek 102025 SeasonJon Hoefling8-677-69-3Tyler Dragon8-676-70-3Blake Schuster7-772-61-3Lorenzo Reyes8-671-77-3Chris Bumbaca8-667-79-3Jordan Mendoza4-1057-60-2Richard MorinN/A25-12-1

Jaguars vs. Chargers live odds, moneyline, over/under

Opening Lines

  • Spread: Chargers (-1.5)
  • Moneyline: Chargers (-238), Jaguars (+200)
  • Over/Under: 49.5

Get the edge with our exclusive NFL betting picks

Jaguars vs. Chargers picks against the spread

Jon Hoefling: Jacksonville Jaguars (+3)

The defense we saw from the Chargers last week was not indicative of their ability to cover.

Tyler Dragon: Los Angeles Chargers (-3)

The Chargers had one of their best wins over the season in Week 10. Can Los Angeles carry that momentum into Week 11? A four-game winning streak entering a Week 12 bye would be huge for Jim Harbaugh’s club.

Christopher Bumbaca: Jacksonville Jaguars (+3)

This will be the “make it make sense” game of the week. If the Jags can get back to forcing some turnovers they could even score the upset.

Lorenzo Reyes: Los Angeles Chargers (-3)

This is a solid matchup for the Chargers, who are taking on a Jags team that completely collapsed against the Davis Mills-led Texans. It is a long trip for the Chargers, but they have the better roster and the better coaching staff.

Jordan Mendoza: Jacksonville Jaguars (+3)

The choke job by Jacksonville couldn’t have come at a worse time. However, it regroups and surprises Los Angeles.

Blake Schuster: Jacksonville Jaguars (+3)

I’m not sold on Jacksonville’s chances outright after last week’s collapse, but I do feel like they’ll be focused enough at home to keep this within a field goal.

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