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Iowa State Cyclones vs. Creighton Bluejays odds, picks and predictions

The Iowa State Cyclones (5-0) and Creighton Bluejays (3-2) tangle Tuesday in Day 2 of the Players Era Festival in Las Vegas, Nevada. The game at Michelob Ultra Arena will tip off at 2 p.m. ET (truTV). Let’s analyze BetMGM Sportsbook’s NCAA basketball odds around the Iowa State vs. Creighton odds and make our expert college basketball picks and predictions for the best bets.

No. 13 Iowa State opened its participation in the 18-team, 3-day tournament Monday vs. the St. John’s Red Storm. The -2.5 Cyclones defeated SJU 83-82 (Over 159). F Milan Momcilovic went 5-of-9 from 3-point range and had 23 points to lead ISU.

Creighton played the Baylor Bears Monday. The 3.5-point-underdog Bluejays lost 81-74 (Over 154.5). Creighton was a minus-15 on the boards.

The teams have met just twice in the last 15 years (2010, 2021), but the Cyclones and Bluejays have met 22 times since 1949. ISU has gone 16-6 over those meetings.

– Rankings: USA TODAY Sports Coaches Poll

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Iowa State vs. Creighton odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:43 a.m. ET.

  • Moneyline (ML): Iowa State -375 (bet $375 to win $100) | Creighton +300 (bet $100 to win $300)
  • Against the spread (ATS): Iowa State -8.5 (-105) | Creighton +8.5 (-115)
  • Over/Under (O/U): 151.5 (O: -115 | U: -105)

Iowa State vs. Creighton picks and predictions

Prediction

Iowa State 78, Creighton 71

No interest; PASS.

Creighton is 6-1 ATS in its last 7 games against an opponent from the Big 12 conference.

The Bluejays are just 1-4 ATS, but they are a high-volume 3-point-shooting squad that had been struggling from distance until shooting 37.9% from beyond the arc in Monday’s loss. Usually solid in rebounding, look for Creighton to bounce back and handle its business in this second game of the tourney.

Iowa State came through a hard-fought Game 1. The Cyclones have been quite good on defense, but contesting perimeter looks is not a point of strength. Peg ISU as being a cut above Creighton from a talent standpoint. But the Bluejays play a slower-than-average style that can compress the score a bit, and the Cyclones don’t figure to get this one to the ATS threshold.

TAKE CREIGHTON +8.5 (-115).

The total has gone Over in 5 of Iowa State’s last 6 games, and in 4 of Creighton’s last 5 when the Bluejays are tabbed as an underdog.

Expect a lot of Creighton 3s and a lot of Iowa State 1s. The Cyclones, who went 20-of-25 (80%) from the free-throw line Monday, have cranked out 25-plus attempts from the stripe in 4 straight games. Both sides figure to get plenty of second-chance buckets also. Look for a score that spirals closer to 160.

BACK THE OVER 151.5 (-115).

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