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Senators vs Blues Prediction, Picks & Same-Game Parlay for Today’s NHL Game

Jake Sanderson has assists in three of his last four games, and our expert NHL predictions expect Sanderson to find the sheet tonight against the St. Louis Blues.

Nov 28, 2025 • 08:52 ET

• 3 min read

Photo By – Imagn Images. Jake Sanderson of the Ottawa Senators.

The Ottawa Senators begin a three-game road trip tonight as they visit the St. Louis Blues at the Enterprise Center. Puck drop is scheduled for 4 p.m. ET.

Jake Sanderson has been productive lately, and my Senators vs Blues predictions are eyeing him to keep it rolling.

Read more in my NHL picks for Friday, November 28.

Senators vs Blues prediction

Senators vs Blues Best bet: Jake Sanderson Over 0.5 assists (+110)

Jake Sanderson is having a nice campaign for the Ottawa Senators. He’s scored four goals and tallied 14 assists in 23 games.

The defenceman is a key piece on both ends of the ice for this squad, and he’s making his presence felt offensively lately.

The 23-year-old has cashed the Over in helpers in three of his last four games. On Wednesday, he was a crucial factor in Ottawa beating the Vegas Golden Knights, scoring once and setting up another two.

Sanderson has also registered at least one assist in five of his previous seven appearances. Last season, he had one helper in two meetings with the St. Louis Blues as well.

He’ll get on the statsheet again tonight with another assist.

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Senators vs Blues same-game parlay

Tim Stutzle is arguably the Senators’ best player, and he’s made that clear over the last few seasons. The German has 11 goals and 12 assists already, and he’s cashed the Over in helpers in two of his previous three.

Against Vegas, Stutzle tallied two assists. He’s registered seven helpers in 12 games on the road this season.

Brady Tkachuk is making his return to the lineup tonight after a lengthy stint on the IR, so there isn’t a ton to back my pick here. However, Tkachuk is one of Ottawa’s main guys, and he’s always a busy player on both ends of the ice. He also had six SOG in two meetings with the Blues in 2024-25.

Senators vs Blues SGP

  • Jake Sanderson Over 0.5 assists
  • Tim Stutzle Over 0.5 assists
  • Brady Tkachuk Over 3.5 shots on goal

Senators vs Blues odds

  • Moneyline: Senators -115 | Blues -105
  • Puck Line: Senators +1.5 (-175) | Blues -1.5 (+220)
  • Over/Under: Over 5.5 (-125) | Under 5.5 (+105)

Senators vs Blues trend

The Ottawa Senators have hit the moneyline in 49 of their last 89 games (+3.00 Units / 3% ROI). Find more NHL betting trends for Senators vs. Blues.

How to watch Senators vs Blues

Location
Enterprise Center, St. Louis, MO

Date
Friday, November 28, 2025

Puck drop
4:00 p.m. ET

TV
TSN5, FDSN Midwest

Senators vs Blues latest injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn’s favorite team is Chelsea FC and he’d like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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