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‘Grey’s Anatomy’ Icon Transforms Into a Tortured Action Hero in First Trailer for Remake of Liam Neeson Thriller

“McDreamy” becomes “McKiller” as Grey’s Anatomy icon Patrick Dempsey is transformed into a tortured action hero for Fox’s new thriller series, which is set to debut early next year. Taking the lead as an action antihero marks a major change for Dempsey, who is best known for being the romantic lead in the long-running medical drama series, as well as roles in various rom-coms.

The series, titled Memory of a Killer, finds Dempsey taking the lead as an elite assassin, Angelo, who, after being diagnosed with early-onset Alzheimer’s, regains his conscience as his memory fades. If that wasn’t already enough to contend with, Angelo discovers that his wife’s recent death may not be an accident, putting him on a vengeful path. And it’s a path he’ll have to walk down quickly.

Produced by Warner Bros. Television and Fox Entertainment and created by Ed Whitmore and Tracey Malone, Memory of a Killer is inspired by the 2003 award-winning Belgian film De Zaak Alzheimer (La Memoire Du Tueur), and stars Michael Imperioli (The Sopranos), Richard Harmon (Final Destination: Bloodlines, The 100), Odeya Rush (Lady Bird), Daniel David Stewart (Reacher), Peter Gadiot (One Piece), and Gina Torres (Serenity, Suits) alongside Dempsey.

‘Memory of a Killer’ Reimagines Liam Neeson’s 2022 Action Thriller for the Small Screen

Memory of a Killer has been described as a combination of “24 and House” by Michael Thorn, President, FOX Television Network, FOX Entertainment, and should be perfect for fans of aged action movie icon Liam Neeson. The series is a serial adaptation, and therefore a remake, of Neeson’s 2022 action thriller Memory, which finds the Taken star as an assassin whose memory is quickly fading. The movie proved to be deeply divisive among critics and audiences, as reflected in its respective Rotten Tomatoes scores of 29% and 80%. Here’s hoping that Memory of a Killer, and Dempsey’s foray into action herodom, fares far better. Memory of a Killer is due to premiere on Monday, January 26, 2026, at 9/8c, and you can check out the official synopsis below…

“Losing your memory is a devastating hammer blow for anyone, but for Angelo Ledda, the stakes couldn’t be higher. His hit man job would be perilous enough, but there’s an added pressure. Angelo lives two totally separate lives — fearsome NYC hitman and sleepy upstate Cooperstown photocopier salesman and father. Having built and maintained a brick wall between his two worlds, Angelo has seamlessly juggled and compartmentalized for years. But now that’s all about to change. Because Alzheimer’s is a foe he can’t outrun, and he knows too well how this ends, as his older brother is already lost to the condition.

Angelo is exceptionally resourceful and talented, the best of the best. But he’s about to be tested like never before — and now every minute counts. This is only made more difficult when he discovers that his wife’s recent death may not have been an accident. So, when someone comes after his daughter — who is pregnant — it’s clear the wall between his lives has been breached. Angelo must stop whoever’s coming for his family by searching his past hits for clues, and the list is very long. Now Angelo must hunt down his mortal enemy while continuing to carry out hits without giving away his diagnosis and still making it home in time to cook dinner for his daughter. Memory of a Killer is a redemptive story about a man who is losing his memory but gaining a conscience. Because Angelo knows he must stop history from repeating itself and save his family — before he forgets the past.”

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