The strikers are part of a side forced largely due to injuries and absences to other key players.
It remains to be seen exactly how Ekitike and Isak will be used, with it possible that they both start as strikers.
That was the case in their only other start together, in the 5-1 thrashing of Eintracht Frankfurt earlier in the competition, when Arne Slot deployed a 4-4-2 of sorts.
Liverpool: Alisson; Gomez, Konate, Van Dijk, Robertson; Szoboszlai, Gravenberch, Mac Allister, Jones; Isak, Ekitike
Substitutes: Mamardashvili, Woodman, Bradley, Lucky, Kerkez, Nyoni, Ngumoha, Wirtz
Inter Milan: Sommer; Akanji, Acerbi, Bastoni; Henrique, Barella, Mkhitaryan, Calhanoglu, Dimarco; Thuram, L.Martinez
Substitutes: J.Martinez, Taho, De Vrij, Zielinski, Sucic, Bonny, Frattesi, Diouf, Augusto, Bisseck, Cocchi, Esposito
Academy defender Wellity Lucky makes the squad for the first time in the Champions League, having made his first-team debut earlier in the campaign during the 3-0 loss to Crystal Palace in the Carabao Cup.
Inter Milan vs. Liverpool is is being shown live on Amazon Prime Video in the UK, which is available to live stream here.
Live audio commentary of Inter Milan vs. Liverpool and a full match replay and highlights will also be available on All Red Video here.
This Is Anfield will also be providing live text commentary throughout on our website and full match reaction and analysis on the This Is Anfield app for iPhone and Android later.
