Top 35 fantasy football QBs for Week 16

Week 16 is here and that means you are vying for a fantasy football championship! Congrats! Below we’ll take a look at who you should start at quarterback this week in your big matchup. Good luck!
Week 16 byes
None.
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QB streamer of the week
Jacoby Brissett, Cardinals vs. Falcons
Brissett has had a great fantasy floor since taking over in Arizona. In nine starts he hasn’t dipped below 18.7 fantasy points. He’s passed for two or more touchdowns in all but one of those games and his lowest yardage total was 249 last week against the Texans’ great defense. He still threw three touchdowns in that game. He’ll face a much easier pass defense back at home against the Falcons this week.
QB injuries/news
Patrick Mahomes, Chiefs
The big injury news from Week 15 was obviously Patrick Mahomes suffering a torn ACL. He of course is done for the season and with the Chiefs eliminated from the playoffs, they’ll limp through the last three games of the year with Gardner Minshew at the helm. He will make it tough for the Chiefs to put up many fantasy points, but Rashee Rice should remains startable.
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Tyrod Taylor, Jets
Taylor injured his groin and Brady Cook has taken over at quarterback last week. Taylor and Justin Fields are dealing with injuries, but we don’t yet what Week 16 will bring at the QB position. We wait with bated breath.
Geno Smith, Raiders
Smith has multiple injuries he’s dealing with at this point in the season, but the most recent is his shoulder. Kenny Pickett started for him last week and did zilch. If he can play, Smith will probably be back this week against the Texans. No matter what, you don’t want to start whoever the Raiders trot out there.
Jayden Daniels, Commanders
Daniels has been shut down for the rest of the season. Marcus Mariota will get the rest of the starts as long as he remains healthy.
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Week 16 odds
Highest point totals
Steelers at Lions (51.5)
Bengals at Dolphins (50.5)
Chargers at Cowboys (49.5)
Patriots at Ravens (47.5)
Falcons at Cardinals (47.5)
Lowest point totals
Raiders at Texans (37.5)
Chiefs at Titans (37.5)
Jets at Saints (40.5)
Bills at Browns (42.5)
Highest implied individual team totals
Lions (29)
Bills (26.5)
Cowboys (26)
Bengals (26)
Texans (26)
49ers (26)
Lowest implied individual team totals
Raiders (11.5)
Browns (16)
Titans (17)
Jets (18)
Commanders (19)
Largest point spreads
Raiders at Texans (-14.5)
Bills (-10.5) at Browns
Eagles (-6.5) at Commanders
Steelers at Lions (-6.5)
49ers (-5.5) at Colts
2025 Fantasy Football Rankings powered by FantasyProsECR ™ – Expert Consensus Rankings




