Vikings at Chargers: Predictions, picks and odds for NFL Week 8 game

The Minnesota Vikings (3-3) visit the Los Angeles Chargers (4-3) at SoFi Stadium in Inglewood for a Week 8 showdown, and USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Thursday, October 23, including live updated odds and injury report news.
NameWeek 72025 RecordJon Hoefling10-558-47-3Blake Schuster9-655-50-3Tyler Dragon8-751-53-3Chris Bumbaca6-949-56-3Lorenzo Reyes10-550-55-3Jordan Mendoza8-739-37-2Richard MorinN/A16-12-1
Chargers vs. Vikings live odds, moneyline, over/under
Opening Lines
- Spread: Chargers (-3)
- Moneyline: Chargers (-162), Vikings (+136)
- Over/Under: 44.5
Get the edge with our exclusive NFL betting picks
Jon Hoefling: Minnesota Vikings (+3)
Don’t overreact to the Vikings’ loss to Philadelphia. The Vikings started to pick their offense back up in the second half of that game. Plus, it’s still hard to back the Chargers given that they’ve lost three of their last four and almost lost to the Dolphins as well.
Jordan Mendoza: Los Angeles Chargers (-3)
Things haven’t been so great for both teams recently, so a win is really needed. The Vikings defense is feeling too hard to trust against Justin Herbert.
Tyler Dragon: Los Angeles Chargers (-3)
We won’t get the Jim Harbaugh and J.J. McCarthy reunion game that we hoped. Carson Wentz has played well filling in. However, this has the makings of a bounce-back game for the Chargers.
Lorenzo Reyes: Los Angeles Chargers (-3)
Losers of three of their last four, the Chargers have a solid get-right situation at home against a struggling Vikings offense. The injuries have piled up, but I have a hard time seeing Minnesota’s middle-of-the-pack offense covering this.
Richard Morin: Los Angeles Chargers (-3)
Feels like a game the Chargers need to win, so I think they’ll show up.
Christopher Bumbaca: Minnesota Vikings (+3)
The NFC is 25-13 against the AFC this season. I’ll take the points here but don’t know if the Vikings can pull it out straight-up.
Chargers vs. Vikings updated injury report
NFL Week 8 picks, predictions odds
Vikings at Chargers | Dolphins at Falcons | Bears at Ravens | Browns at Patriots | Giants at Eagles | 49ers at Texans | Bills at Panthers | Jets at Bengals | Buccaneers at Saints | Titans at Colts | Cowboys at Broncos | Packers at Steelers | Commanders at Chiefs




