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LA Lakers at Memphis Grizzlies odds, picks and predictions

The LA Lakers (3-2) face the Memphis Grizzlies (3-2) Friday with tip-off from FedExForum in Memphis, Tennessee, set for 9:30 p.m. ET (Prime Video). Let’s analyze BetMGM Sportsbook’s NBA odds around the Lakers vs. Grizzlies odds and make our expert NBA picks and predictions for the best bets.

2024-25 season series: Lakers won 3-1

G Austin Reaves played the hero again for the Lakers on Wednesday night, draining a 12-foot jumper at the buzzer to cap a 28-point performance and lift L.A. past the Minnesota Timberwolves 116-115. The Lakers won outright as 7.5-point road underdogs as the Over (224.5) hit. Reaves, who scoed 41 and 51 points in the last 2 games, also had 16 assists. F Jake LaRavia added 27 points and 8 rebounds in the victory.

G Ja Morant delivered in the clutch Wednesday night, sinking an 11-foot jumper with 7.6 seconds left to lift the Grizzlies over the Phoenix Suns 114-113. Memphis failed to cover as 2-point road favorites as the Under (242) hit. Morant led all scorers with 28 points while F Santi Aldama added a double-double off the bench (14 points, 10 rebounds).

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Lakers at Grizzlies odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:47 a.m. ET.

  • Moneyline (ML): Lakers +105 (bet $100 to win $105) | Grizzlies -130 (bet $130 to win $100)
  • Against the spread (ATS): Lakers +1.5 (-105) | Grizzlies -1.5 (-115)
  • Over/Under (O/U): 238.5 (O: -110 | U: -110)

Lakers at Grizzlies key injuries

Lakers

  • G Luka Doncic (knee/finger) questionable
  • F LeBron James (back) out
  • G Marcus Smart (quad) questionable

Grizzlies

  • G Ty Jerome (calf) out
  • G Scotty Pippen Jr. (toe) out

For most recent updates: Official NBA injury report.

Lakers at Grizzlies picks and predictions

Prediction

Lakers 122, Grizzlies 118

I’m riding with the LAKERS (+105) when they head to Memphis for NBA Cup group play. Even without James, Los Angeles has found its groove behind Reaves, who’s been electric — averaging 34.2 points, 5.6 rebounds, and 10 assists while shooting over 52% from the field and nearly 39% from deep. He’s keeping the offense humming despite the absence of Doncic, and JJ Redick’s offensive structure has given this short-handed Lakers team a steady rhythm.

The Lakers have taken 7 of their last 10 games against Memphis, using disciplined defense and controlled pace to frustrate the Grizzlies. They don’t rely on chaos — they pick their spots, crash the boards, and force opponents into tough half-court looks.

Meanwhile, the Grizzlies are still banged up, missing key rotational depth players Pippen and Jerome. Without their full backcourt rotation, Memphis struggles when the pace slows or when physical teams dictate tempo — exactly how L.A. plays under Redick.

The Lakers’ chemistry, composure, and star-level execution make them the smarter pick here. Expect another efficient Reaves performance and the Lakers to grind out a road win under the Halloween lights in Memphis.

PASS.

If you’d feel more comfortable taking 1.5 points feel free, but I’d rather take the plus odds on the moneyline.

BET OVER 238.5 (-110).

This matchup screams Over and history says it’s worth a shot. The Over has hit in 7 of the last 8 meetings between these teams. The Lakers have gone Over in 7 of their last 8, and Memphis has done it in 4 of their last 6. Expect fireworks Friday night.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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