Las Vegas Raiders vs Denver Broncos picks, predictions, odds for NFL Week 10 game Thursday

NFL Overreactions Week 9
USAT’s Prince Grimes breaks down the biggest storylines from NFL Week 9.
Sports Seriously
The Las Vegas Raiders and Denver Broncos play on Thursday, Nov. 6, at the Broncos’ Empower Field at Mile High in a game on the NFL Week 10 schedule.
Which team will win the NFL Week 10 game on Thursday Night Football?
Check out these NFL Week 10 picks and NFL Week 10 predictions for the game, which can be seen at 6:15 p.m. MST on Prime Video (stream on Amazon).
The Broncos are a 9.5-point favorite over the Raiders in NFL Week 10 odds for the game, courtesy of BetMGM Sportsbook.
Denver is -550 on the moneyline, while Las Vegas is +400. The over/under (point total) is set at 42.5 points.
NFL Week 10 picks: Raiders at Broncos | Falcons vs Colts | Saints at Panthers | Giants at Bears | Jaguars at Texans | Bills at Dolphins | Ravens at Vikings | Browns at Jets | Patriots at Buccaneers | Cardinals at Seahawks | Rams at 49ers | Lions at Commanders | Steelers at Chargers | Eagles at Packers | Score predictions
Watch Raiders at Broncos live on Prime Video
Jeremy Cluff writes: “The Broncos currently have a 6-game win streak, tied for the longest in the NFL. It will be seven games after Thursday Night Football in NFL Week 10. Denver’s defense will feast on Geno Smith.”
Bookies.com: Bet the under in Broncos vs Raiders game
Bill Speros writes: “The Broncos ripped off their 6th straight win Sunday, taking down the host Texans 18-15 in overtime after a Will Lutz field goal. The Broncos have gone under the points total in 6 of 9 games, including under 41.5 on Sunday. They’ve covered just 4 times and have yet to cover on a number larger than 7 points. This line of 10 points doesn’t fit the projected total of 42.5. When in doubt, take the under in our Week 10 NFL Best Bets.”
The site’s formula predicts that the Broncos will win the NFL Week 10 game against the Raiders.
ESPN: Broncos have a 73.6% chance to beat Raiders on Thursday Night Football
The site gives the Raiders a 26.2% shot at winning the NFL Week 10 game, with the remaining percentage accounting for a tie.
Dimers: Broncos 25, Raiders 19
It writes: “After extensive simulations, our model gives the Raiders a win probability of 25%, while the Broncos have a win probability of 75%.”
Sportsnaut: Denver Broncos 27, Las Vegas Raiders 17
Matt Johnson writes: “The good news for the Las Vegas Raiders in this Thursday Night Football matchup versus the Denver Broncos is that Brock Bowers is healthy. It’s an enticing matchup for the All-Pro, as one of the few vulnerabilities on this Broncos defense is its pass coverage versus tight ends (482 receiving yards and 13.0 yards per reception allowed). The good fortune ends there for Las Vegas. Denver comes into Week 10 with a league-high 40 sacks and the Raiders offensive line can’t hold up in pass protection. On top of that, Las Vegas has allowed 122.3 rushing yards per game in its last six contests. The Broncos should win this one comfortably.”
NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team
Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.
Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don’t miss a thing.




