What we’re hearing on the Bills: QB Josh Allen will look to continue his historic commanding performances against the Dolphins. In 15 games with Allen starting against Miami, the Bills have averaged 32.5 points per game, the fifth-highest team mark by a starting QB against a single opponent in the Super Bowl Era (since 1966). This is also a prime game for Allen to score another rushing touchdown (has had two in each of the past two games) as Miami has allowed four rushing touchdowns to QBs, second most in the league. — Alaina Getzenberg
What we’re hearing on the Dolphins: QB Tua Tagovailoa took responsibility for his play this season — which he said falls well below the standard he has set in previous seasons — but, when asked, he stopped short of saying he’s playing for his job. Coach Mike McDaniel said earlier this week that the team is “certain” Tagovailoa is the best option against the Bills, but he left things relatively open-ended after this week: “We play the players that give us the best chance to win, and when that changes or if that changes or if somebody else gives us a better shot, then we adjust there.” — Marcel Louis-Jacques
Stat to know: Tagovailoa’s 11 interceptions so far is tied for the most in the NFL with the Raiders’ Geno Smith. With another pick, Tagovailoa would be first Dolphins QB since Chad Henne in 2010 (12) with 12 or more interceptions in his first 10 games of a season. — ESPN Research
Bold prediction: The Bills will keep running back De’von Achane from picking up long gains in the passing game. Buffalo is second in DVOA against running backs as receivers, and it kept Achane to just 29 yards on seven catches when these teams met in Week 3. — Schatz
Fantasy nugget: Bills tight end Dalton Kincaid has averaged 16.0 fantasy points in the four games this season in which he has seen at least six targets. Even though he splits snaps with two other TEs (Dawson Knox and Jackson Hawes), Kincaid leads the group in routes run, which is what matters most for fantasy production. He’s in an excellent spot against a defense that allows the fifth-most fantasy points per game to TEs. See Week 10 rankings. — Moody
Betting nugget: The Bills are 1-4 ATS in their past five games as favorites. Read more. — ESPN Research
Maldonado’s pick: Bills 27, Dolphins 10
Moody’s pick: Bills 38, Dolphins 17
Schatz’s pick: Bills 27, Dolphins 16
FPI prediction: BUF, 69.6 (by an average of 7.5 points)
