Giants vs. Patriots prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats
Jaxson Dart is set to return Monday Night when the Giants (2-10) take on Drake Maye and the New England Patriots (10-2) in Foxborough.
The Patriots, riding a nine-game win streak, are heavy favorites against the Giants, who have lost six straight and who were the lone team eliminated from playoff contention prior to Thanksgiving.
After being sidelined the last two weeks, Dart (concussion) returns as QB1 for the Giants. The rookie has brought excitement and hope to the Giants, but that has yet to translate into wins.
The Patriots’ head into their bye week following Monday’s game. The time off is necessary for a Patriots’ offensive line dealing with injuries, including losing two starters to injured reserve earlier this week.
The Giants enter the week following a 34-27 loss to the Detroit Lions. Following another late game collapse, Defensive Coordinator Shane Bowen was fired by interim Head Coach Mike Kafka. Bowen’s issues went well beyond the loss to the Lions. The Giants have lost five games this season in which they held a lead of at least 10 points. They have also given up a league-high 133 points in the fourth quarter.
The Patriots’ ninth straight win was last week in Cincinnati. Maye, the second-year signal caller for New England, led the Pats to a 26-20 win throwing for 294 yards and a touchdown.
Lets take a deeper dive into Monday Night Football and the matchup between the Giants and the Patriots.
NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from DraftKings, player news and updates courtesy of Rotoworld, and of course our predictions and best bets for the game from our staff of experts.
Game Details and How to watch the Giants vs. Patriots live Monday
- Date: Monday, December 1, 2025
- Time: 8:15PM EST
- Site: Gillette Stadium
- City: Foxborough, MA
- Network/Streaming: ESPN
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Game odds for the Giants at the Patriots
The latest odds as of Sunday courtesy of DraftKings:
- Moneyline: Giants (+320), Patriots (-410)
- Spread: Patriots -7.5
- Total: 46.5 points
This game opened at Patriots -7.5 with the Game Total set at 47.5.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NFL schedule!
Quarterback Matchup for New York at New England
- Giants Starting QB: Jaxson Dart
Last Game: 11/9 at Chicago – 19-29, 242yds, 0TDs, 0INTs, Sacked 2 times, 6 carries for 66yds rushing
Season: 9GP, 128-204, 1417yds, 10TDs, 3 INTs, Sacked 21 times, 57 carries for 317yds rushing - Patriots Starting QB: Drake Maye
Last Game: 11/23 at Cincinnati – 22-35, 294yds, 1TD, 1INT, Sacked 1 time, 5 carries for 22yds, rushing
Season: 12GP, 252-355, 3130yds, 21TDs, 6INTs, Sacked 37 times, 75 carries for 307yds rushing
NFL Week 13 Preview: Giants vs. Patriots
At 10-2, the Patriots have the exact opposite record as the 2-10 Giants, and with New England favored at home by a touchdown, Mike Florio and Chris Simms both like them to cover against New York in Week 13.
Giants at Patriots team stats, betting trends
- The Patriots are 4-2 at home this season
- The Giants are 0-7 on the road this season
- The Patriots are 7-4-1 ATS this season
- The Giants are 7-5 ATS this season
- The Giants have covered the spread in 4 of their last 5 road games against teams with better records
- 6 of the Giants’ last 7 games (86%) have gone OVER the Total
- TreVeyon Henderson has five touchdowns (rushing and receiving combined) since Week 10
- The Giants have scored 20 or more points in seven consecutive games (tied for the second-longest single-season streak in franchise history since 2000)
- Brian Burns is second in the NFL with 13 sacks
Giants Player Injuries
- LB Kayvon Thibodeaux (shoulder) has been declared OUT for Monday’s game
- S Anthony Johnson Jr. (undisclosed) has been declared OUT for Monday’s game
- LB Victor Dimukeje (knee) is listed as questionable for Monday’s game
- LB Demetrius Flannigan-Fowles (neck) is listed as questionable for Monday’s game
- CB Korie Black (biceps) is listed as questionable for Monday’s game
Patriots Player Injuries
- LT Will Campbell (knee) has been placed on IR and is OUT for Monday’s game
- C Jared Wilson (ankle) has been ruled OUT of Monday’s game
- S Brenden Schooler (ankle) has been ruled OUT of Monday’s game
- CB Alex Austin (undisclosed) has been placed on IR and is OUT for Monday’s game
- DT Khyiris Tonga (chest) is listed as questionable for Monday’s game
- LB Harold Landry III (knee) is listed as questionable for Monday’s game
Rotoworld Best Bets
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Giants might give Patriots trouble if Dart returns
Trysta Krick and Jay Croucher are wary of the seven-point spread when the Patriots host the Giants in Week 13.
Our model calculates projections around each moneyline, spread and over/under bet for every game on the NFL calendar based on data points like past performance, player matchups, stadium information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Best bets our model is projecting for this week’s game between the Giants and the Patriots
- Moneyline: NBC Sports Bet is staying away from a play on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on the New York Giants at +7.5.
- Total: NBC Sports Bet is staying away from a play on the Game Total of 46.5.
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Follow our experts on socials to keep up with all the latest content from the staff:
● Jay Croucher (@croucherJD)
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● Vaughn Dalzell (@VmoneySports)
● Trysta Krick (@Trista_Krick)
