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Knicks vs. Celtics odds, line: Proven model reveals picks for NBA matchup on December 2

The New York Knicks will look to extend their winning streak to five games when they battle the Boston Celtics in an Atlantic Division matchup on Tuesday night. New York is coming off a 116-94 win over the Toronto Raptors on Sunday, while Boston downed Cleveland 117-115 that same day. The Knicks (13-6), who have won seven of their last 10, are just 3-5 on the road this season. The Celtics (11-9), who are third in the Atlantic Division, are 6-4 on their home court. New York forward OG Anunoby (hamstring) will miss the game.

Tip-off from TD Garden in Boston is set for 8 p.m. ET. The Celtics lead the all-time series 308-191, but the Knicks earned a 105-95 win on Oct. 24. Boston is a 1.5-point favorite in the latest Knicks vs. Celtics odds from SportsLine consensus, while the over/under for total points scored is 230.5.

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Before making any Knicks vs. Celtics picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine’s model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 7 of the 2025-26 NBA season on a sizzling 29-14 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Knicks vs. Celtics 10,000 times and the results are in. We can tell you that the model is going Over on the point total, and it also says one side of the spread hits in nearly 70% of simulations!

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