Striker Dominic Calvert-Lewin replaces injured winger Daniel James as Leeds make four changes from the 3-2 weekend defeat to Manchester City.
Under pressure manager Daniel Farke appears to have moved into a back five for Chelsea.
The visitors have made five changes with Moises Caicedo serving the first of a three game ban after his red card in the 1-1 draw with Arsenal.
Leeds XI: Perri, Bogle, Bijol, Rodon, Struijk, Gudmundsson, Stach, Tanaka, Ampadu, Nmecha, Calvert-Lewin
Subs: Darlow, Justin, Gruev, Bornauw, Aaronson, Gnonto, Harrison, Okafor, Piroe
Chelsea XI: Sanchez, Chalobah, Tosin, Badiashile, Cucurella, Andrey Santos, Fernandez, Estevao, Joao Pedro, Gittens, Delap.
Subs: Jorgensen, Acheampong, Hato, Gusto, James, Palmer, Neto, Garnacho, Guiu
