Spurs vs. Cavaliers Prediction, Odds and Best NBA Prop Bets for Friday, Dec. 5

The Cleveland Cavaliers are looking to get back on track when they host the San Antonio Spurs on Friday night.
Cleveland has lost four of its last five games to fall to 13-10 on the season, while the Spurs have won two straight, four of five, and seven of nine to improve to 15-6 on the year.
The oddsmakers have the Cavaliers as home favorites at the best betting sites on Friday night.
Let’s take a look at the odds, players to watch and my prediction for Friday night’s NBA matchup.
Odds via DraftKings Sportsbook
Spread
Moneyline
Total
Spurs Injury Report
Cavaliers Injury Report
De’Aaron Fox OVER 24.5 Points (-119)
De’Aaron Fox has taken a bigger role in the Spurs’ offense this season since Victor Wembanyama got hurt. He’s averaging 25 points per game, up from the 19.7 per game in 17 contests with San Antonio last year.
Fox missed the start of the season and only had 58 points in his first three games. Since then, he’s averaged 26.7 points per game and has put up at least 25 in eight of his last nine games, including three straight.
The guard should be able to keep that up tonight in Cleveland.
The Spurs are rolling right now while the Cavaliers are in a rut. It’s the perfect opportunity for San Antonio to get its first win in Cleveland since March 2021.
Going on the road hasn’t been too much of a challenge for the Spurs, who are 6-4 away from home. The Cavaliers are a respectable 8-5 at home, but they’re struggling as of late, with home losses to the Trail Blazers (as -10 favorites) and Celtics (as -7.5 favorites).
I’ll take the Spurs outright on the road, although +4.5 is certainly the safer play.
Pick: Spurs moneyline (+154)
Odds refresh periodically and are subject to change.
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