Thomas Frank makes two changes to the side that beat Brentford at the weekend.
Randal Kolo Muani and Rodrigo Bentancur drop to the bench with Joao Palhinha and Wilson Odobert given the nod.
Mathys Tel is on the bench after receiving a late call up to replace Dominic Solanke in Spurs’ Champions League squad.
Tottenham XI: Vicario, Palhinha, Simons, Richarlison, Gray, Romero, Kudus, Porro, Spence, Odobert, Van de Ven
Subs: Kinsky, Gunter, Danso, Tel, Bergvall, Sarr, Bentancur, Davies, Kolo Muani, Scarlett, Olusesi, Williams-Barnet
Slavia Prague XI: Stanek, Zima, Ogbu, Chaloupek, Holes, Sanyang, Sadilek, Provod, Moses, Doudera, Chytil
