Rob Edwards makes four changes with Wolves still looking for their first Premier League win of the season.
Jose Sa, Ki-Jana Hoever, Santi Bueno and Fer Lopez are all handed starts
Toti and Sam Johnstone miss out while Emmanuel Agbadou has joined Ivory Coast for the Africa Cup of Nations for and Yerson Mosquera is banned.
Wolves XI: Sa, Hoever, Doherty, S Bueno, Krejci, Wolfe, Andre, J Gomes, Lopez, Hwang, Strand Larsen
Subs: Johnstone, Tchatchoua, Pond, Olagunju, Rawlings, Gonzalez, Mane, Arias, Arokodare
Striker Igor Thiago wins his fitness battle and starts for Brentford.
The 12-goal forward was rated touch and go by boss Keith Andrews with a knock – missing the 2-0 Carabao Cup quarter-final defeat at Manchester City on Wednesday – but will lead the line at Molineux.
Rico Henry, Yehor Yarmoliuk and Kevin Schade start but Jordan Henderson is only fit enough for the bench.
Brentford XI: Kelleher, Kayode, Collins, Van Den Berg, Henry, Jensen, Yarmoliuk, Janelt, Schade, Thiago, Lewis-Potter
Subs: Valdimarsson, Hickey, Pinnock, Henderson, Ajer, Damsgaard, Konak, Nunes, Donovan
