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Alexei Popyrin vs. Matteo Berrettini prediction, odds, picks for ATP Vienna Open 2025

Alexei Popyrin and Matteo Berrettini will lock horns in the round of 32 of the ATP Vienna Open event on Wednesday.

Based on the latest simulations, Dimers’ advanced tennis model predicts Matteo Berrettini as the most likely winner of the match.

“We have simulated the outcome of Wednesday’s Popyrin-Berrettini match 10,000 times,” said Dimers data analyst Greg Butyn.

“With the latest updates and numerous other variables, we estimate Matteo Berrettini’s chance of winning at 60%, with Alexei Popyrin at 40%.”

For expanded analysis of Wednesday’s match, including best bets and picks, visit our interactive Popyrin vs. Berrettini predictions page.

Popyrin vs. Berrettini prediction: Who will win and advance to the round of 16?

Using powerful machine learning and data, we have simulated the outcome of Wednesday’s Popyrin-Berrettini men’s singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Berrettini a 60% chance of beating Popyrin at the ATP Vienna Open tournament.

Additionally, Berrettini has a 56% chance of winning the first set. The simulations also show Berrettini (-1.5) has a 53% chance of covering the games spread, while the under 25.5 games has a 59% chance of hitting, according to our model.

 

Alexei Popyrin vs. Matteo Berrettini odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type
Popyrin
Berrettini

Moneyline
+130
-150

First Set
+110
-139

Game Spread
-1.5 (-120)
+1.5 (-110)

Total Games
o25.5 (-120)
u25.5 (-120)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Popyrin vs. Berrettini picks and best bets

Our model’s strongest edge in today’s Popyrin vs. Berrettini match is on the first set.

Our expert predictions, aligned with the best odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Popyrin vs. Berrettini updates and essential details

The ATP Vienna Open match between Alexei Popyrin and Matteo Berrettini is scheduled to commence on Wednesday at 7:30AM ET.

  • Who: Alexei Popyrin vs. Matteo Berrettini
  • Date: Wednesday, October 22, 2025
  • Approx. Time: 7:30AM ET/4:30AM PT
  • Tournament: ATP Vienna, Austria Men’s Singles 2025
  • Round: Round of 32

All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.

Dimers’ full preview of Wednesday’s Popyrin vs. Berrettini match includes our prediction, picks and the latest betting odds.

Before making any Alexei Popyrin vs. Matteo Berrettini picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

Conclusion

We predict Matteo Berrettini, with a 60% win probability, will likely beat Alexei Popyrin at the ATP Vienna Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Popyrin vs. Berrettini insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on Tennis

Stay up-to-date with the latest tennis news and parlay picks throughout the year. Plus, Dimers’ ATP and WTA world rankings showcase our in-house approach to accurately ranking every men’s and women’s player in the world.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

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