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Knicks vs. Bucks odds, line: Proven model reveals picks for NBA matchup

Teams coming off losses meet when the New York Knicks battle the Milwaukee Bucks in a key early-season Eastern Conference matchup on Tuesday night. New York dropped a 115-107 decision to the Miami Heat on Sunday, while Milwaukee dropped a 118-113 loss to the Cleveland Cavaliers that same night. The Knicks (2-1), who are second in the Atlantic Division, are 0-1 on the road this season. The Bucks (2-1), who are tied for second in the Central Division, are 1-0 on their home court in 2025-26.

Tip-off from Fiserv Forum in Milwaukee is set for 8 p.m. ET. The Bucks lead the all-time series 125-110, but the Knicks have won the past five meetings. New York is a 2.5-point favorite in the latest Knicks vs. Bucks odds from SportsLine consensus, while the over/under for total points scored is 229.5.

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Before making any Knicks vs. Bucks picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine’s model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past seven seasons. The model enters Week 2 of the 2025-26 NBA season on a sizzling 161-120 roll on all top-rated NBA picks, returning nearly $4,000. It also went 24-11 (69%) on top-rated NBA against-the-spread picks last season. Anyone following could have seen HUGE returns!

The model has simulated Knicks vs. Bucks 10,000 times and the results are in. We can tell you that the model is going Under on the point total, and it also says one side of the spread hits in well over 50% of simulations!

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