The Toronto Raptors ruled out the fourth-year guard ahead of Thursday’s game against the Cleveland Cavaliers with lower back spasms.
Agbaji also missed Tuesday’s win over the Brooklyn Nets.
In nine games this season, he is averaging just 2.7 points per contest while struggling from three-point range at an 8.3 per cent clip.
It will be the third game this season that the rookie has missed after sitting out the opening two games with a forearm injury.
The 20-year-old has been a solid presence on both ends for the Raptors, averaging 8.8 points, 3.9 rebounds, 1.2 assists and 1.4 steals+blocks per game while shooting 49.2 per cent from the floor and 50 per cent from deep.
Meanwhile, Sandro Mamukelashvili (neck contusion, stiffness) was made available for the tilt against the second-place Cavaliers (8-4) after being listed as questionable.
Toronto has won five of its last six after a slow start to the season to sit 6-5 overall.
