It has not been the most comfortable of starts to the autumn internationals for both Ireland and Australia.
Andy Farrell’s side opened the month with defeat to the All Blacks in Chicago followed by last week’s unconvincing win over Japan in Dublin.
For the Wallabies, their European tour has seen defeats to England and Italy leaving the tourists in a run of bad form with just one win in their last six games.
Ireland have named Mack Hansen a full-back and recalled Sam Prendergast at fly-half for Saturday’s match as Farrell makes nine changes from the side that beat Japan 41-10 last week.
Hansen, who was not expected to feature at all this month after picking up an injury on duty for Connacht, finds himself starting in the 15 jersey for the first time for Ireland with Hugo Keenan and Jamie Osbourne on the sidelines.
For 22-year-old Prendergast, it is a first start since Ireland’s Six Nations defeat to France in March, having been been locked in a battle for the jersey with Jack Crowley over the last 12 months.
Stuart McCloskey returns from injury while Paddy McCarthy earns his first Test start following his debut against New Zealand and a try-scoring cameo against Japan.
James Lowe, Jamison Gibson-Park, Dan Sheehan, Tadhg Furlong and Jack Conan are the others recalled to the starting team.
For Australia, Schmidt has opted to give James O’Connor his first northern hemisphere Test appearance in four years as he starts at fly-half.
He’ll partner Jake Gordan in the half-backs with Len Ikitau (centre) and Max Jorgensen (full-back) returning to the starting side with Ulster-bound Angus Bell joining Allan Alaalatoa in the front row.
Full teams
Ireland: M Hansen, T O’Brien, R Henshaw, S McCloskey, J Lowe; S Prendergast, J Gibson-Park; P McCarthy, D Sheehan, T Furlong ; J Ryan, T Beirne; R Baird, C Doris (capt), J Conan.
Replacements: R Kelleher, A Porter, T Clarkson, C Prendergast, N Timoney, C Casey, J Crowley, B Aki.
Australia: M Jorgensen; F Daugunu; JA Suaalii, L Ikitau; H Potter; J O’Connor, J Gordon; A Bell, M Faessler, A Alaalatoa; J Williams, T Hooper; R Valetini, F McReight, H Wilson (capt)
Replacements: B Pollard, T Robertson, Z Nonggorr, N Frost, C Tizzano, R Lonergan, T Edmed, A Kellaway.
Coverage details
The match kicks off at 20:10 GMT.
There will be live radio coverage from 20:00 GMT on BBC Radio Ulster and BBC Sounds with live text commentary on the BBC Sport website.
We’ll have further reaction and analysis from former Ireland star Conor Murray on the Ireland Rugby Social podcast after the match too (available on BBC Sounds).
