Strasbourg make three changes to the side that lost to Lens on the weekend with former Brighton player Julio Enciso making a start.
Ex-Chelsea left-back Ben Chilwell takes a spot on the bench.
Strasbourg XI: Penders; Doue, Hogsberg, Sarr, Barco; Doukoure, El Mourabet; Moreira, Enciso, Nanasi; Emegha.
Subs: Bajic, Kerckaert, Omobamidele, Chilwell, Panichelli, Paez, Amougou, Godo, Amo-Ameyaw, Nzingoula, Lemarechal, Rafael Luis.
Crystal Palace also make just three changes from their 2-0 Premier League win over Wolves. Daichi Kamada, Adam Wharton and Chris Richards drop to the bench.
Jaydee Canvot, Will Hughes and Jefferson Lerma are given starts.
Crystal Palace XI: Henderson; Canvot, Lacroix, Guehi; Munoz, Hughes, Lerma, Mitchell; Sarr, Mateta, Pino.
Subs: Matthews, Benítez, Nketiah, Uche, Clyne, Kamada, Wharton, Esse, Richards, Devenny, Cardines.
