Emi Martinez starts for Aston Villa against his former club.
The goalkeeper was injured in the warm-up ahead of Wednesday’s 4-3 win at Brighton, but makes a quick recovery.
Youri Tielemans is in for Evann Guessand, who is left out of the squad.
Aston Villa XI: Martinez, Cash. Konsa, Torres, Maatsen, Onana, Tielemans, Kamara, McGinn, Rogers, Watkins
Substitutes: Bizot, Lindelof, Digne, Garcia, Bogarde, Hemmings, Buendia, Malen, Sancho
Bukayo Saka, Eberechi Eze and Jurrien Timber return for Arsenal at Villa Park.
The trio were rested for the 2-0 win over Brentford on Wednesday and replace Noni Madueke and Gabriel Martinelli, who drop to the bench, while Cristhian Mosquera is out for up to six weeks with an ankle injury.
Mikel Arteta also names 16-year-old defender Marli Salmon among the substitutes.
Arsenal XI: Raya, White, Timber, Hincapie, Calafiori, Zubimendi, Rice, Odegaard, Saka, Eze, Merino
Substitutes: Arrizabalaga, Salmon, Martinelli, Gyokeres, Norgaard, Trossard, Madueke, Nwaneri, Lewis-Skelly
