Champions League Best Bets: Picks, Odds & Predictions for Wednesday, Nov. 5

Champions League best bets for Wednesday, Nov. 5 include Athletic Club vs Newcastle United, Borussia Dortmund vs Real Madrid, FC Barcelona vs Club Brugge and Atalanata vs. Marseille.
Matchday 4 in the UEFA Champions League will end Wednesday with another nine-game slate. This time teams such as FC Barcelona, Newcastle United, Manchester City and Borussia Dortmund will see action. The battle between Manchester City and Dortmund at the Etihad Stadium stands out as one of the marquee games of the slate.
Knowing injuries and predicted lineups (and eventually confirmed) for Champions League matches is always useful before betting matches. Check out our lineups page to get all the info.
Match Bet Odds Newcastle United vs. Athletic Club Newcastle to Win & Both Teams Don’t Score +116 Manchester City vs. Borussia Dortmund Over 3.5 Total Goals +112 Club Brugge vs. FC Barcelona Marcus Rashford Anytime Goalscorer +114 Marseille vs. Atalanta Marseille to Win +119
UEFA Champions League SGP for Athletic Club at Newcastle United
Newcastle to win and both teams don’t score +116
Newcastle United have turned things around after losing in their Champions League debut against FC Barcelona in St. James’ Park, scoring seven goals and conceding none in their last two victories against Royale Union SG (4-0) and Benfica (3-0). The Magpies are riding an impressive four-game winning streak at home, with three clean sheets over that period. Don’t be surprised if they repeat that feat here, as they’ll be facing an Athletic Club side that will be considerably weakened ahead of this match.
The Basque team is missing several key players, such as Oihan Sancet (leg), Nico Williams (groin), Inaki Williams (groin) and Yuri Berchiche (undisclosed). Athletic have struggled even when fit this season in Europe, winning just one of three matches (L2) and losing their lone away tilt 4-1 against Dortmund. Athletic have also gone winless in their last five away from home in all competitions (D1, L4).
UEFA Champions League over/under bet for Borussia Dortmund at Manchester City
Over 3.5 total goals +112
If there’s one thing that has characterized Dortmund during the early stages of the UEFA Champions League, it’s that their matches have been filled with goals. They opened their campaign with a 4-4 draw against Juventus and later clinched high-scoring wins over Athletic Club (4-1) and Copenhagen (4-2). Their goalscoring ability is beyond any doubt, though they are defensively lacking.
Pep Guardiola’s men have scored at least two goals in every Champions League match thus far, and they should have enough quality to unsettle a Dortmund defense that has yet to keep a clean sheet in Europe. This figures to be a back-and-forth contest, so there’s a real chance that Dortmund can keep their streak of high-scoring matches in the Champions League alive in this trip to the Etihad Stadium.
FC Barcelona at Club Brugge Betting and Goalscoring Odds
As has been the trend in recent weeks, Barcelona will once again be shorthanded in this match, though that shouldn’t take away their status as favorites for this contest. Los Blaugranas know neither Robert Lewandowski nor Lamine Yamal are 100 percent in terms of fitness, and they’re also missing two key players in Pedri (strain) and Raphinha (thigh). However, one player they could rely on to make an impact is Rashford.
The Englishman has taken advantage of the absence of Raphinha, and he’s been at his best in the Champions League. He netted a brace in the 2-1 win over Newcastle at St. James’ Park, assisted in Barca’s lone goal against PSG and added another brace against Olympiacos. With five goal contributions in three European matches, look for Rashford to make an impact again on Belgian soil.
UEFA Champions League Best Bets for Atalanta at Marseille
Marseille to win +119
Marseille and Atalanta will clash in a battle between two teams desperate to secure a win in the European stage. Marseille are coming off a 2-1 loss to Sporting CP and have dropped two of their first three matches. Atalanta played out a disappointing 0-0 draw at home against Slavia Prague last time out, and they enter this game on a six-game winless streak across all competitions following their 1-0 loss at Udinese in Serie A this past weekend.
Marseille have the edge of playing at home, and considering Marseille’s excellent run at home that has seen them go undefeated in 14 of their last 15 competitive matches here at Stade Vélodrome, expect the hosts to have enough in them to secure the victory in this match.
Champions League Betting Picks Wednesday, November 5
- Newcastle United vs. Athletic Club: Newcastle to win and both teams don’t score +116
- Manchester City vs. Borussia Dortmund: Over 3.5 total goals +112
- Club Brugge vs. FC Barcelona: Marcus Rashford to score anytime +114
- Marseille vs. Atalanta: Marseille to win +119
Question Answer What are the best Champions League bets for Wednesday, Nov. 5? Our top plays are Newcastle to win and both teams don’t score, Over 3.5 goals in Man City vs Dortmund, Marcus Rashford to score anytime for Barcelona, and Marseille to beat Atalanta. What time do Champions League matches start Wednesday? Most fixtures kick off at 3:00 p.m. ET (8:00 p.m. GMT), with select early matches beginning at 12:45 p.m. ET. Where can I find the latest Champions League odds? Visit our Champions League odds page for live lines from DraftKings, FanDuel, BetMGM and other sportsbooks. Who is favored in the marquee match of the day? Manchester City enter as strong favorites against Borussia Dortmund.
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