Week 11 of the NFL season is already upon us, and the challenge of setting lineups and finding an edge in fantasy football only becomes greater than the week before.
While talent and matchups always matter, one of the most reliable indicators of fantasy potential comes from the betting market. High over/unders signal expected scoring, and more points on the board generally translate to more opportunities for fantasy production. Every touchdown and red-zone trip boosts the chances for quarterbacks, running backs, receivers, tight ends and even kickers to deliver starter-worthy numbers.
This week’s slate offers several matchups with enticing totals. A handful of contests stand out as potential fantasy goldmines, making them worth targeting when finalizing lineups. Below are the games, along with some included fantasy football analysis and advice.
*Over/under totals obtained from FanDuel Sportsbook*
This Week 11 clash between Dallas and Las Vegas sets up as a fantasy-friendly matchup as defense might be optional. The Cowboys allow the second-most yards per game (397.4). Although the Raiders are much better defensively, they’ve still struggled in spots this season. Dak Prescott is a high-end start against a vulnerable Raiders secondary, while Geno Smith is a deeper-league flier with some sneaky upside. Ceedee Lamb is a must-start and could feast on volume, with George Pickens and Tre Tucker both offering strong WR2 and flex appeal, respectively. Tyler Lockett is more of a flex option, but he is capable of commanding volume as he was the Raiders’ leading receiver on Thursday night after Jakobi Meyers was traded. Brock Bowers is an automatic start, and Jake Ferguson remains a steady TE1 with red-zone potential. Finally, Javonte Williams and Ashton Jeanty are both primed for big games in what should be a balanced game script.
Nov 2, 2025; Paradise, Nevada, USA; Las Vegas Raiders tight end Brock Bowers (89) celebrates after scoring a touchdown during the second half against the Jacksonville Jaguars at Allegiant Stadium. Mandatory Credit: Stephen R. Sylvanie-Imagn Images / Stephen R. Sylvanie-Imagn Images
Quarterbacks:
Dak Prescott – Start
Geno Smith – Deeper League Play
Running Backs:
Javonte Williams – Start
Ashton Jeanty – Start
Wide Receivers:
Ceedee Lamb – Must Start
George Pickens – Start
Tre Tucker – Start
Tyler Lockett – Flex
Tight Ends:
Brock Bowers – Must Start
Jake Ferguson – Start
This Week 11 matchup is tied for being the anticipated highest-scoring matchup of the week. Josh Allen is a must-start as always, and Baker Mayfield is a near must-start even with many of his top playmakers potentially sidelined. James Cook is coming off one of his lesser performances, but he is still a must-start. Rachaad White (or Bucky Irving if active) is primed for a big day, as the Bills allow the third-most rushing yards per game (147.6) and are coming off a week in which De’Von Achane rushed for 174 yards and two TDs. Emeka Egbuka is a mid-tier WR1 option, with Tez Johnson, Khalil Shakir and Keon Coleman all viable flex plays. At tight end, Dalton Kincaid remains a near-weekly starter, and Cade Otton provides steady TE1 value with strong performances over his last five games. Expect plenty of passing volume and fantasy-friendly production on both sides in what could be one of the week’s most entertaining games.
Nov 9, 2025; Tampa, Florida, USA; Tampa Bay Buccaneers wide receiver Emeka Egbuka (2) runs for a gain past New England Patriots safety Craig Woodson (31) and cornerback Marcus Jones (25) during the first quarter at Raymond James Stadium. Mandatory Credit: Jonathan Dyer-Imagn Images / Jonathan Dyer-Imagn Images
Quarterbacks:
Josh Allen – Must Start
Baker Mayfield – Start
Running Backs:
James Cook – Must Start
Bucky Irving (Q)/Rachaad White – Start
Ollie Gordon II – Bench
Wide Receivers:
Emeka Egbuka – Start
Tez Johnson – Flex
Khalil Shakir – Flex
Keon Coleman – Flex
Chris Godwin (Q) – Bench
Tight Ends:
Dalton Kincaid – Start
Cade Otton – Start
This Week 11 NFC showdown features fantasy studs across the board and plenty of scoring potential. Jalen Hurts is a must-start thanks to his dual-threat dominance, while Jared Goff remains a reliable QB2 play coming off a big game vs. the Commanders in a likely shootout. Both backfields are loaded, as Saquon Barkley and Jahmyr Gibbs are automatic starts, and David Montgomery’s goal-line role keeps him firmly in play. The wide receiver talent is elite, with A.J. Brown and Amon-Ra St. Brown as set-and-forget stars, with DeVonta Smith and Jameson Williams offering explosive WR2 upside. Tight ends Sam LaPorta and Dallas Goedert should both benefit from heavy red-zone involvement in what projects as one of the most fantasy-rich matchups of the week. The analysis is simple: start the studs in this one.
Oct 19, 2025; Minneapolis, Minnesota, USA; Philadelphia Eagles wide receiver A.J. Brown (11) makes a catch during the first half against the Minnesota Vikings at U.S. Bank Stadium. Mandatory Credit: Jeffrey Becker-Imagn Images / Jeffrey Becker-Imagn Images
Quarterbacks:
Jalen Hurts – Must Start
Jared Goff – Start
Running Backs:
Saquon Barkley – Must Start
Jahmyr Gibbs – Must Start
David Montgomery – Start
Wide Receivers:
A.J. Brown – Must Start
Amon-Ra St. Brown – Must Start
DeVonta Smith – Start
Jameson Williams – Start
Tight Ends:
Sam LaPorta – Start
Dallas Goedert – Start
This divisional matchup features two of the NFL’s hottest teams and can quietly turn into a high-scoring affair despite both teams boasting top defensive units. Matthew Stafford is a near lineup-lock with 20 TDs and zero INTs over his last six games, while Sam Darnold is a high-end QB2 option despite oftentimes being limited on opportunities. Kyren Williams remains a low-end RB1 with touchdown upside, and Kenneth Walker plus Zach Charbonnet both hold flex value despite Walker’s conferencing goal-line usage. The wide receivers are where this game gets fun. Puka Nacua and Jaxon Smith-Njigba are must-starts, while Davante Adams brings WR1 potential as he has six touchdowns in his last three games. Cooper Kupp is more of a risky flex but still capable of a vintage performance in this revenge game. Tight ends can be avoided this week, as AJ Barner is highly touchdown dependent, and Tyler Higbee doesn’t carry much fantasy relevance.
Nov 2, 2025; Inglewood, California, USA; Los Angeles Rams wide receiver Davante Adams (17) runs after the catch against the New Orleans Saints during the second half at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images / Jayne Kamin-Oncea-Imagn Images
Quarterbacks:
Matthew Stafford – Start
Sam Darnold – Start
Running Backs:
Kyren Williams – Start
Kenneth Walker – Flex
Zach Charbonnet – Flex
Wide Receivers:
Puka Nacua – Must Start
Jaxon Smith-Njigba – Must Start
Davante Adams – Start
Cooper Kupp – Flex
Rashid Shaheed – Bench
Tight Ends:
AJ Barner – Bench
Tyler Higbee – Bench
This NFC West matchup may not appear as glamorous as others on the slate, but it features several relevant fantasy options despite uncertainty at quarterback. Both Mac Jones (or Brock Purdy) and Jacoby Brissett are deeper-league plays, but the real appeal lies with the skill positions. Christian McCaffrey remains an automatic start. Trey Benson (or Bam Knight if Benson sits) is a viable RB2 option, with Emari Demercado holding flex appeal in PPR formats. Marvin Harrison Jr., Jauan Jennings and Ricky Pearsall (if active) are all starters against beatable secondaries, while George Kittle and Trey McBride headline one of the week’s best tight end matchups. Expect steady scoring and plenty of fantasy relevance across the board.
Nov 9, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) runs the ball against Los Angeles Rams safety Quentin Lake (37) during the second quarter at Levi’s Stadium. Mandatory Credit: Cary Edmondson-Imagn Images / Cary Edmondson-Imagn Images
Quarterbacks:
Brock Purdy (Q)/Mac Jones – Deeper League Play
Jacoby Brissett – Deeper League Play
Running Backs:
Christian McCaffrey – Must Start
Trey Benson (Q)/Bam Knight – Start
Emari Demercado – Flex
Brian Robinson Jr. – Bench
Michael Carter – Bench
Wide Receivers:
Marvin Harrison Jr. – Start
Jauan Jennings – Start
Ricky Pearsall (Q) – Start
Michael Wilson – Bench
Kendrick Bourne – Bench
Tight Ends:
George Kittle – Must Start
Trey McBride – Must Start
