Wing Kerr Johnston will make his first Glasgow Warriors start away to Scarlets on Saturday evening.
The 21-year-old has not featured since making his debut as a substitute nine months ago.
Ten of the 23-man squad were involved in Scotland’s autumn internationals, although Sione Tuipulotu, Kyle Steyn, Scott Cummings, Rory Darge, Jack Dempsey and Jamie Dobbie are rested, along with Zander and Matt Fagerson.
Ollie Smith gets a run at outside centre, combining with captain for the day Stafford McDowall.
Scrum-half Ben Afshar makes his first start of the season after coming off the bench in the past two United Rugby Championship matches.
Scarlets sit rock bottom of the table after four successive defeats, while the Warriors lie third with four wins from their five outings.
“We are excited to kick off an important block of fixtures over the next 10 weeks,” said head coach Franco Smith.
“The whole squad has worked hard over the last couple of weeks to put ourselves in the best possible position, as we know that the way we apply ourselves will be extremely important.”
Glasgow Warriors: McKay, Rowe, Smith, McDowall, Johnston, Lancaster, Afshar; Bhatti, Matthews, Schickerling, Craig, Oguntibeju, Brown, Fraser, Duncan.
Replacements: Hiddleston, McBeth, Talakai, Williamson, Samuel, Miller, Horne, Hastings.
