Mega Millions winning numbers for Tuesday, Oct. 21. Check tickets for $650 million jackpot

Odds of winning the Powerball and Mega Millions are NOT in your favor

Odds of hitting the jackpot in Mega Millions or Powerball are around 1-in-292 million. Here are things that you’re more likely to land than big bucks.

• The winning numbers for the October 21 Mega Millions drawing were 2, 18, 27, 34, 59, and the Mega ball was 18.
• One ticket sold in Illinois won $3 million by matching the five white balls with the Megaplier.
• The jackpot for the next drawing on Friday has grown to an estimated $680 million.

The results are in for the 10th-largest jackpot ever in the Mega Millions lottery game.

The jackpot has been rolling since it was last won at $348 million in Virginia on June 27. A ticket sold in Ohio for the April 18 drawing won a $112 million prize before that, according to megamillions.com.

Here are the numbers drawn and prizes won in the Oct. 21 drawing:

Mega Millions winning numbers for 10/21/2025 lottery drawing

Here are the Tuesday, Oct. 21, Mega Millions winning numbers: 2, 18, 27, 34 and 59. The gold Mega ball is 18. The Mega Millions lottery jackpot was an estimated $650 million with a cash option of $304.1 million for Tuesday night’s drawing.

Did anyone win the Mega Millions jackpot?

No one won the jackpot in Tuesday night’s Mega Millions drawing. One ticket, sold in Illinois, matched the five white balls to win the second-tier prize; with the 3X multiplier, it is worth $3 million.

What is the Mega Millions jackpot up to?

Friday’s jackpot is estimated to be $680 million with a cash option of $318.2 million. This is the ninth largest jackpot since the game started in 2002.

When is the next Mega Millions drawing?

The next drawing is Friday, October 24, at 11 p.m. ET.

What time is the Mega Millions drawing?

Drawings are every Tuesday and Friday at 11 p.m. ET.

What is the largest Mega Millions jackpot?

The largest Mega Millions jackpot won on a single ticket is a $1.602 billion prize won in Florida on Aug. 8. Other large single-ticket Mega Millions prizes have been $1.537 billion won in South Carolina on Oct. 23, 2018; $1.348 billion won in Maine on Jan. 13, 2023; $1.337 billion won in Illinois on July 29, 2022 and $1.050 billion won in Michigan on Jan. 22, 2021.

How to play the Mega Millions lottery

Mega Millions tickets cost $2 per play. 

There are nine ways to win a prize, from the jackpot to $2. 

Players can pick six numbers from two separate pools of numbers: five different numbers from the white balls numbered 1-70 and one number from the gold balls numbered 1-25.

• 5 + 1 = Jackpot.
• 5 + 0 = $1 million.
• 4 + 1 = $10,000.
• 4 + 0 = $500.
• 3 + 1 = $200.
• 3 + 0 = $10.
• 2 + 1= $10.
• 1 + 1 = $4.
• 0 + 1 = $2.

You win the jackpot by matching all six winning numbers in a drawing. 

You can pick your lucky numbers or select Easy Pick or Quick Pick and have the numbers auto-drawn. If you can’t decide, the Mega Millions website has a random number generator.

What is the Mega Millions Megaplier?

Most states offer the Megaplier feature, which increases non-jackpot prizes from two, three, four and five times.

It costs an additional $1 per play. 

Before each regular Mega Millions drawing, the Megaplier is drawn. From a pool of 15 balls, five are marked with “2X,” three with “4X” and one with “5X.”

Where to buy Mega Millions tickets

You can play Mega Millions in 47 localities: 45 states, plus the District of Columbia and the U.S. Virgin Islands. To find locations, search the Mega Millions website.

In Kentucky, Ohio and Indiana, you can buy a Mega Millions ticket at gas stations, convenience stores and supermarkets until 10:45 p.m. on drawing night.

In Kentucky, residents can also purchase tickets online at kylottery.com.

In Ohio, residents can use the Lottery Card available in Kroger, Buehler’s Fresh Foods and Giant Eagle stores. It allows Ohio consumers to enter draw games on their phones and get notified and paid electronically if they win.

What are the odds of winning the Mega Millions jackpot?

The odds of winning the Mega Millions jackpot are about 1 in 290 million. 

The overall chance of winning any prize is 1 in 23.